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doi: 10.1093/geront/gnad067 [DOI] [PMC free article] [PubMed] [Google Scholar] 530

GLP-1 receptor agonists are also being increasingly prescribed for weight loss and management

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[1] [2] This effect is particularly pronounced early in treatment, though it may diminish somewhat with continued use

For example, efpeglenatide, a long-acting GLP-1 RA and an exendin analog linked to an IgG4 Fc fragment, has been explored for once-monthly administration to treat type 2 diabetes.197,198 Additionally, efforts have been made to develop oral formulations with improved bioavailability ( F )