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PLX4032, a selective BRAFV600E kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAFWT melanoma cells

34 ChesnokovaV.ZhouC.Ben-ShlomoA.ZonisS.TaniY.RenS

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This Cleveland Clinic retrospective cohort study included 7,881 adult patients with an average body mass index (BMI) greater than 39, which is classified as clinically severe obesity