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Furthermore, its short half-life of less than 3 h (Min et al., 2025) necessitates twice-daily injections to maintain efficacy, which can be a limiting factor for long-term patient adherence

Those with diabetes saw slightly lower weight loss percentages at 3 months but gained the additional benefit of significant blood sugar improvements

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Elevated IGF-1 levels have been associated with increased risk of certain cancers, fluid retention, and joint pain

Both of these approaches are dangerous and unnecessary

& Rorsman, P