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Antioxidant Protection: Helping to defend cells against oxidative stress and environmental damage

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Increases in resting heart rate are a recognised class effect of incretin-based therapies and have been reported with GLP-1 receptor agonists more broadly, as reflected in the Summary of Product Characteristics (SmPC) for licensed agents such as semaglutide (Wegovy) and liraglutide (Saxenda)

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In addition, GLP-1RAs have the potential to preserve or improve pancreatic -cell function [33,34]

Despite significant progress, the effective translation of these findings into clinical practice remains a challenge