By blocking K+ channels, GLP-1 depolarizes the cell and causes calcium influx, and thus causes exocytosis of insulin from the beta-cell
Bri (00:49:40): But other than that, I was actually pretty surprised based off social media, how sick people were, in the bathroom all the time, this and this, and that was a hard thing starting too
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The pattern is particularly noticeable in people taking 7.5 mg or higher, where the absolute increase in peak concentration is more significant
This table shows the numbers and proportions of participants with experience of serious adverse events, categorised by system organ classes, regardless of treatment
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