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The dipeptidyl peptidase-IV inhibitor inhibits the expression of vascular adhesion molecules and inflammatory cytokines in HUVECs via Akt- and AMPK-dependent mechanisms

Subsequent work documented prolonged GH and IGF-1 stimulation in Phase 1/2 clinical trials (PMID 16352683) and characterised once-daily administration profiles (PMID 16822960)

Wound healing A number of animal studies and clinical trials have shown that GHK-Cu facilitates skin repair and wound healing

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