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In these STEP trials, most participants experienced mild to moderate symptoms, with the incidence of severe side effects being 9.8% in the semaglutide treatment group and 6.4% in the placebo group

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doi: 10.3945/ajcn.115.121269 159 YiannakouILongMTJacquesPFBeiserAPickeringRTMooreLLet al

Med 67 , 445452 (1996)

Rotate injection sites with each weekly dose to minimize the risk of local reactions and injection site irritation

TABLE 8 In vivo -studies using kunming mice