(2025) trial specifically tested semaglutide as an add-on to AID systems and found a 4.8 percentage point improvement in time in range (from 69.4% to 74.2%) alongside an 11.3-unit daily reduction in insulin, without any increase in hypoglycemia
Readout is expected in Q2-Q3 2026
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These shifts help strengthen gut barrier integrity and reduce systemic inflammation, which are both key to improving insulin sensitivity and reducing appetite (Singh et al, 2024)
