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It was found that the maximal mean weight loss relative to placebo was -3.06, -6.15, -7.45, and -5.5kg after 1 year with mean weight regain +0.48kg, +0.91kg, +1.27kg, +0.43kg the following year, respectively

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Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat

Thus, among these four molecules (auranofin, shikonin, ebselen, and allicin), auranofin is potentially the most active at inhibiting bacteria in a bactericidal capacity

10.1126/science.1164680 131