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Additionally, significant decreases in triglycerides and cholesterol were observed, highlighting Berberines beneficial impact on lipid metabolism

(35) Conclusion GLP-1 receptor agonists are becoming integral to obesity and diabetes management, with significant implications for orthopedic surgery

Burak Altintas, MD, an orthopedist with UTMB, who was not involved in this study, further highlighted the following limitations of the research: The limitations include retrospective design and likely residual confounding despite matching as fracture risk is influenced by many variables that are not reported [] Further, the comparison group is heterogeneous, combining another GLP-1 receptor agonist (dulaglutide) with two mechanistically different weight-loss medications