No FDA-approved human dose exists for either peptide, so there is no correct dose to state only what investigators used under monitoring
Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss
PD patients and animal models exhibit decreased CoQ 10 levels (100, 101)
doi: 10.1080/1028415X.2022.2146843 Summary Keywords intermittent fasting, immune system, immunomodulatory effect, metabolic syndrome, obesity Citation He Z, Xu H, Li C, Yang H and Mao Y (2023) Intermittent fasting and immunomodulatory effects: A systematic review
doi: 10.1038/s41598-021-82917-7 77 PhillipsDCWoollardKJGriffithsHR
The other is it can break down in stomach acid, requiring the body to put it back together (which is nutrient intensive)