Moreover, Ex-4 induces autophagy and attenuates ovarian cancer cell viability by upregulating the expression of autophagic markers beclin-1 and microtubule-associated proteins light chain 3I/II (LC3I/II), while simultaneously downregulating the expression of p62 (a linker protein for LC3II) [68]
Inflammopharmacology 31 (1), 221230
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Heterologous expression of an engineered bifunctional bacterial GSH biosynthetic enzyme (GshF) in mitochondria enables mitochondrial GSH production and ameliorates the metabolic and proliferative defects caused by its depletion
