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Research suggests that GLP-1 medications are associated with reductions in vitamin B12 levels over time

The attention deficit and hyperactivity of CCAS patients [6] resemble the increased spontaneous activity of Lurcher mice in the open field and hole-board tests [177, 179, 180]

It occurs in about 10% of the general population with 83% of these patients between 25 and 65 years of age

Both mechanisms increase cytoplasmic concentrations of dopamine (DA), norepinephrine (NE), and serotonin (5-HT), producing a cytoplasmic surge of monoamines