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This review examines studies on iron metabolism, regulation via the hepcidin-ferroportin pathway, myocardial energy, oxidative stress, and clinical trials of iron supplementation or reduction in heart failure, chronic kidney disease, the elderly, women, and athletes

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However, supplementation has become a popular alternative for those seeking to increase their antioxidant capacity

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Common conditions that may support medical necessity for supplements include nutritional deficiencies, gut and digestive concerns, metabolic and hormonal conditions, musculoskeletal issues, and immune dysfunction