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The inactive form is considered a precursor as it gets converted into an active peptide GLP-1 (7-37) by cleaving a single arginine residue (Fig

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Finally, obesity is associated with worse response to drugs for PsO (Table S1 additional material).29,30 Hidradenitis suppurativa and obesity There is a higher prevalence of obesity in subjects with HS than in the general population,31,32 and HS is detected more frequently in children with obesity.33 The association between HS and obesity, as is the case for PsO, is also bidirectional, with low-grade inflammation as the unifying thread