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Symptoms of severe GI bleeding includes: Stomach pain Heartburn Bloody vomit Vomit with brown granules like coffee grounds Blood in stools Black or tarry stools Combining alcohol and ibuprofen increases your risk and severity of GI bleeds

Can a B12 injection help with tiredness even if I havent been diagnosed with a deficiency

Accordingly, it has issued new advice to check vitamin B12 serum levels in patients being treated with metformin who have symptoms suggestive of vitamin B12 deficiency.[] The proposed mechanisms to explain metformin-induced vitamin B12 deficiency among patients with T2DM include alterations in small bowel motility, which stimulates bacterial overgrowth and consequential vitamin B12 deficiency, competitive inhibition or inactivation of vitamin B12 absorption, alterations in IF levels, and interaction with the cubulin endocytic receptor

Vitamin B12 is water-soluble, meaning excess amounts are usually excreted by the body

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