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The difference is that we use fewer sessions for treatment

Mol Cell Biochem 1999 Oct;200(1-2):93-102 [abstract] Imai S, Matsui K, Nakazawa M, Takatsuka N, Takeda K, Tamatsu H

According to a recent systematic review, supplementation with vitamin A, C, B12, B3, B6, and D (with or without calcium), multivitamins, selenium, and calcium does not reduce the risk of overall or cardiovascular mortality.78 The US Preventive Services Task Force does not recommend the use of vitamins or multivitamins to prevent cardiovascular disease or cancer.78 Indeed, it advises against beta-carotene supplementation, as there is evidence that it might increase the risk of lung cancer and overall and cardiovascular mortality

Patients interested in these medications should consult healthcare providers to determine the best option based on their health profile and treatment goals

doi: 10.1038/s41586-021-03539-7

Benefits and risks of hormone replacement therapy (HRT)