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Homocysteine catabolism is conducted by cystathionine -synthase (CBS), an enzyme dependent on pyridoxal-5-phosphate (derived from vitamin B 6 ), which allows the condensation of homocysteine with serine (Fig

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Recurrent pyogenic cholangitis Recurrent pyogenic cholangitis is characterized by recurrent bouts of cholangitis secondary to stricturing of the biliary tree, biliary obstruction, and formation of primary intrahepatic pigment stones