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Mice from a different substrain and vendor, but fed similar lean and high-fat diets to this study, showed a predominance of the family Erysipelotrichaceae, of which Ileibacterium is a genus, in their cecal microbiomes 76

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When timed correctly, 5-Amino-1MQ preloads the cellular NAD+ pool, and MOTS-c administered 46 hours later has the cofactor availability to fully activate AMPK-dependent pathways

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