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Temporary side effects mild swelling, light redness, or small bumps at injection points typically resolve within a few hours to two days

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Manufacturers build microneedle patches using stick-to-skin tapes and films , such as silicone, hydrocolloid, hydrogel, and other skin-friendly materials that can embed or carry microneedles

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This pain-context-specific behavioral reinforcement establishes that the rewarding effect is contingent upon the relief of neuropathic pain, rather than a general rewarding effect