The project co-led by Timothy Marlowe, PhD, associate professor in the Department of Internal Medicine , the U of A Cancer Center and the College of Pharmacy, Michael Fallon, MD, FACP , executive director for Clinical Research and chair of the Department of Internal Medicine, and Hyo Jin Park, PhD, assistant research scientist in the Department of Internal Medicine targets the connection between focal adhesion kinase (FAK) and paxillin, two proteins that become hyperactive during fibrosis and fuel the buildup of scar tissue in the liver
Neither of the candidates seemed suitable for the job
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Furthermore, although this study highlighted the potential of these compounds to counter chemotherapy resistance, the combined effects of 6-thio-dG with standard chemotherapeutic agents remain unexplored, warranting future studies on synergistic interactions to establish optimal combination therapies
Gastroenterology 148:13921404.e21
10.3390/ijms23010305 Int
