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This legal framework remains in effect and is regularly reviewed by the agency to ensure public safety

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A 2026 systematic review of 37 studies found that discontinuing treatment was associated with weight regain of roughly half a pound per month, with researchers projecting a return to baseline weight within about 1.5 years

It also has profound protective benefits for the kidneys

Current treatments primarily focus on symptom management, with limited efficacy in halting or reversing disease progression