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Doctors must look at these to figure out the best treatment

Vitamin B12: How Frequently Should I Get It

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Older individuals (with aging, some individuals dont absorb vitamin B12 as well)

Casado, M., Vallet, V

When you swallow a B12 pill, several steps have to work for it to be absorbed: stomach acid and the enzyme pepsin must release B12 from food or the supplement, the stomach must secrete a protein called intrinsic factor that binds to B12, and the B12-intrinsic factor complex must reach the ileum (the end of the small intestine) where it is finally absorbed