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S.DostertC.NonnenmacherY.CoxM.et al (2017)

AD is characterized by two core pathologies, formation of amyloid- plaques and neurofibrillary tangles

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Notably, SLC25A39-associated genes localized predominantly to the inner mitochondrial membrane and were involved in critical mitochondrial processes, including ATP synthesis-coupled electron transport, assembly of mitochondrial respiratory chain complex I, and electron transfer from NADH to ubiquinone (Fig