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In this 52-week trial of 1,698 people with type 2 diabetes whose blood sugar wasn't adequately controlled on Metformin, orforglipron outperformed oral semaglutide on every primary and secondary endpoint, including A1C reduction and weight loss, with improvements visible as early as four weeks

The particles were dried using a Nafion dryer (Perma Pure Inc.), and the RH prior to entering the CCN counter was kept below 20%, as confirmed by an RH probe (Omega, RH-USB)

Baseline control for the Dose-finding experiment was the average from 6 sessions from the same days of the Baseline weeks as the drug administration days (Wednesdays)

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