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The review also documented how GCL expression is transcriptionally upregulated by electrophiles through antioxidant response elements (ARE/EpRE) in the GCLC and GCLM promoters establishing the Nrf2/ARE pathway as the master regulator of GSH biosynthetic capacity under stress conditions

Copper metabolism and cuproptosis: broad perspectives in the treatment of hepatocellular carcinoma

PubMed Sikiric, P., Seiwerth, S., Rucman, R., Kolenc, D., Vuletic, L.B., Drmic, D., Grgic, T., Strbe, S., Zukanovic, G., Crvenkovic, D., Madzarac, G., Rukavina, I., Sucic, M., Baric, M., Staroveski, M., Zoric, Z., Turkalj, I., & Aralica, G

It is known for its ability to regenerate glutathione, helping your body maintain higher levels for longer periods

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Anti-Aging Effects As the master antioxidant, glutathione neutralizes free radicals before they damage cells and DNA