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All procedures were reviewed and approved by the Institutional Animal Care and Welfare Committee of CIGB

We have previously developed a drug repurposing workflow to identify metabolic drug targets that, if depleted, inhibit the growth of cancer cells without harming healthy tissues

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High affinity also results in lower yields as target molecules may not dissociate from the ligand during elution

Feeling cold on retatrutide is most likely due to loss of insulating body fat and reduced caloric intake, both of which lower the body's capacity to generate and retain heat

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