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Preclinical studies suggest that prophylactic TNF- inhibition eliminated ICI-induced colitis without affecting anti-tumor response (241)

Figure 1 2.1 The core enzymatic triad: BCAT4, MAM1, and CYP79F1 The commitment of methionine to aliphatic glucosinolate synthesis is driven by three pivotal enzymes, each executing a distinct and non-redundant step in the construction of the glucoraphanin backbone ( Figure 2 )

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doi: 10.1080/10715762.2019.1666983 21 ZhangYSwandaRVNieLLiuXWangCLeeHet al

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In nature, GHK is found in blood plasma as well as in saliva and urine