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Mutational studies have been done focusing mainly on catalytically important small subunit residues to develop variants with improved catalytic activity

Results Figure 1 describes our selection of studies using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) format

It was engineered isolate hGHs lipolytic (fat-breaking) properties without activating the growth hormone receptor or increasing IGF-1. The design allows it to mimic hGHs metabolic domain in a shorter, more stable form

Increased concentration of H 2 O 2 may contribute to the development of tumor but proved to be toxic when reaches to much higher level

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