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Beyond compromising quality of life, AF notably augments the risks of adverse clinical outcomes and mortality by predisposing patients to complications such as thromboembolism and heart failure (1, 2)

Report Serious Symptoms If you notice symptoms of a serious side effect, contact your doctor immediately

Furthermore, a marked decline of IGF-I has also been related to a higher probability of hepatocarcinoma[217] and poorer prognosis in patients requiring liver surgery[218]

The information below is provided for educational purposes only and reflects a risk-minimization, medical-first perspective

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Adapted from the Society of Clinical Research Associates 2 Impact of Usability Issues on Clinical Trial Data Conducting HF validation tests before major clinical trials, as recommended by the FDA, supports more reliable trial outcomes by identifying usability issues early in development