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The respiratory control ratio (RCR), a key measure of coupling efficiency (V3/V4), was significantly increased by DSIP at 10 and 10 M concentrations, suggesting tighter coupling between respiration and phosphorylation

These types of reactions often look like small red spots or a mild heat-like rash and usually subside as the body finds its new balance

All average concentrations were higher than those in the plasma

In addition, it has been demonstrated that GGT-overexpressing cells were more resistant to hydrogen peroxide [67] and chemotherapics, such as doxorubicin [68], cisplatin [64], and 5-fluorouracil [69]

doi: 10.1016/j.jmb.2007.11.034

Related to Nrf2, a potential target for redox chemotherapy is HO-1