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Alongside glycemic control, it is indicated to reduce the risk of major adverse cardiovascular events cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke in adults with type 2 diabetes and established cardiovascular disease, and to reduce the risk of sustained eGFR decline, end-stage kidney disease, and cardiovascular death in adults with type 2 diabetes and chronic kidney disease

If persistent gastrointestinal symptoms occur, patients should consult their prescribing clinician to ensure appropriate dose titration and symptom management

2 eClinical Medicine

Obesity pharmacotherapy reduces food intake and enhances satiety without the need to alter meal timing (62, 63), thus avoiding the potential health risks and reward-based eating behaviors reportedly associated with IF (44, 45)

HCPCS (2026) HCPCS Level II codes for enteral/parenteral nutrition are governed by CMS DME Coverage Policy Article A52491

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