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Early pharmacological studies characterized Sermorelin's dose-response relationships, showing that doses as low as 1 mcg/kg can stimulate significant GH release, with maximal responses typically achieved at doses of 1-3 mcg/kg in diagnostic testing contexts

[1] [2] In 2024, Wegovy also received FDA approval to reduce cardiovascular risk in adults with established cardiovascular disease and either obesity or overweight

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All animals were treated humanely, and all studies were carried out in accordance with good laboratory practice (GLP) (China Food and Drug Administration, CFDA) guidelines for nonclinical laboratory studies of drugs issued by the National Scientific and Technological Committee of the Peoples Republic of China