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In a series of experiments in monkeys with obesity and diabetes, the tri-agonist SAR441255 showed superior metabolic outcomes to that achieved with a comparator dual GLP-1/GCG RA
However, given that this study did not measure IL-6 or IL-10, it is unclear where there was also a concomitant increase in anti-inflammatory molecular factors to counteract this response
Providers may prescribe compounded medications when appropriate
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