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Shake flask culture with addition of amino acid precursors Genetic manipulation and medium optimization together with the addition of amino acid precursors are required to increase GSH production

Surgeons will remove the appendix using one of two methods: open or laparoscopic surgery

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doi: 10.1186/s12933-018-0728-6 3 US Food and Drug Administration

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While these methods offer significant potential, their clinical translation is often hindered by the requirement for specialized equipment and the risk of skin irritation