Kitaguchi et al
Some of the indicators of oxidative damage that have been observed in the striatum and cerebral cortex of patients with HD are an increase in the concentration of malondialdehyde (MDA) and 4-hydroxynonenal (lipid oxidation products), increase in carbonylation and in protein nitration, as well as a decrease in GSH and an increase in the activity of glutathione peroxidase, catalase, and superoxide dismutase [184]
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It does seem as though thats when creatine seems to shine in the brain
