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Knowledge about cerebrovascular involvement in neurological disorders is rapidly expanding, and increasing evidence indicates that defects in angiogenesis, and the bloodbrain boundary are causally related to the cognitive dysfunctions that may be found in the course of neurodegenerative disorders (Nicolakakis and Hamel 2011

Gaunt DM, Brigden A, Harris SRS, Hollingworth W, Jago R, Solomon-Moore E, et al

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Advocates of compounding stress that the practice has been around for a long time and that the FDA permits it to preserve vital access to medication

124,125 Another example of genetic primary astrocytopathy is the Duchenne muscular dystrophy (DMD) caused by mutations in the gene encoding dystrophin, which in the CNS is present almost exclusively in astrocytes