RS induces cellular senescence, which hampers cell reproduction and proliferation in response to damage, and senescent cells develop a phenotype characterized by the secretion of factors like interleukins, chemokines, matrix metalloproteases (MMPs), and extracellular matrix (ECM) proteins [15]
doi: 10.1073/pnas.0407881102 230 RattiA.GuminaV.LenziP.BossolascoP.FulceriF.VolpeC.et al
Another aspect on a unique role of IGF-1R in cancer is based on several recent findings that loss of suppressor oncogenes as well as activation of proto-oncogenes is related to IGF-1R function and activity (Baserga, 1994
Two of them were from the hand-search of the related articles
Science 306 , 19301933 (2004)
4 Enrollment in terminated D-SNP look-alike plans was concentrated in the following three states: Californias 26 terminated D-SNP look-alikes offered by 15 MAOs accounted for nearly 70% of terminated D-SNP look-alike enrollment