Symptoms start and ease later
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First-pass metabolism occurs when a large portion of L-arginine gets broken down by the enzyme arginase in your liver and intestines before it can reach your bloodstream
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For anti-ulcer activity against ethanol-induced stomach mucosal damage, it was diluted in 10% Tween 20 at doses of 62.5, 125, 250, and 500 mg/kg body weight for oral administration as previously described [46]
