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In 2015, p53 was reported to promote ferroptosis through the transrepression of SLC7A11 expression (Jiang et al., 2015)

This change in ion concentration may then trigger a series of events that result in the cell taking action, such as releasing enzymes or producing new proteins

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For example, a 2026 randomized controlled trial found that semaglutide significantly reduced alcohol consumption in treatment-seeking individuals with alcohol use disorder and obesity

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