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FDA Adverse Event Reporting System (FAERS) data may include reports of musculoskeletal symptoms in patients using GLP-1 receptor agonists, though these reports do not establish causation and may reflect coincidental timing rather than a true drug effect

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Indeed, a phase II dose-finding trial demonstrated greater body weight reductions associated with daily subcutaneous semaglutide at a dose greater than 0.2 mg compared with liraglutide 3.0 mg daily [35]