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Semaglutide would typically produce around 33 pounds of weight loss

Phase 3 clinical trial results released in May 2026 showed participants lost up to 28.3% of their body weight over 80 weeks, making it potentially more effective than semaglutide (Ozempic and Wegovy) and tirzepatide (Zepbound and Mounjaro)

The specialty drug management program has improved: access rates for first-time users by over 50% and expedited their first medication fill by two to four days

Following resolution of nationwide shortages, the FDA ended its temporary enforcement discretion, meaning these medications may now only be compounded under limited, legally defined circumstances . On February 21, 2025 , the U.S

Table 1 IBD and metabolic disorders are closely interconnected

Retatrutide isnt approved by the MHRA, so no UK doctor can legally prescribe it privately