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This model has been tested and exhibits good reproducibility

Probiotics are usually indigestible dietary carbohydrates that promote the growth and function of beneficial microorganisms in the gastrointestinal tract (43)

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In patients with severe heart failure (NYHA Class IV), spironolactone has been shown to improve overall survival and NYHA functional class, and to reduce hospitalizations when added to conventional therapy (e.g., ACE inhibitor, loop diuretic, digoxin)

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