The in vitro and in vivo studies showed the effectiveness of curcumin against the pathogenetic mechanisms of MS, and although further evidence from randomized controlled trials on curcumin efficacy is required, its role as an effective alternative treatment was suggested (Ghanaatian et al., 2019)
The studies were conducted using various mouse models to elucidate the role of RAMP1 and RAMP3 in mediating cagrilintides central and metabolic actions [2]
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