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Allan et al used the TriNetX EHR platform to evaluate the risk of developing dry and wet AMD compared with controls in 9,669 patients taking GLP-1 RA medications

It is considered as natural, environmentally friendly, and hypoallergenic

Mechanistically, GPR146 promotes adipogenesis through Gq-PKC-AKT signaling in preadipocytes and enhances lipolytic activity in mature adipocytes via ERK signaling

For diabetes In a 30-week trial involving 388 people who had uncontrolled diabetes, the 1mg weekly dose of Ozempic lowered their long-term blood sugar (HbA1c) levels by 1.6%

Patients should be monitored for diabetic retinopathy complications (especially if on insulin with rapid HbA1c improvement), gallbladder disease, and signs of dehydration or acute kidney injury

It acts as a primary internal defense system against oxidative stress