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In addition, neuroimaging studies of patients with ADHD reported an elevated level of striatal dopamine transporter activity, which is reverted by the administration of methylphenidate [59, 60]

Overview of Iron Metabolism in Health and Disease

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The protocol was approved by the IRB of KNUH with informed consent from the legal guardian of subjects aged 2 years and older

Those designs can help researchers explore possible biological effects, but they do not prove that a home protocol is safe or effective