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Interestingly, we observed no significant change in PAGly (Fig

One is a serious communicable infectious disease ( overfat pandemic , an equally serious global disaster comprised of people with excess body fat ( The condition of overfat, which ultimately is indicative of malnutrition, adversely affects various aspects of health, including impaired innate and adaptive immune responses, promoting chronic inflammation and insulin resistance, leading to chronic diseases

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Moreover, GLP-1R in EAT positively correlates with genes associated with brown adipose tissue activity, FA oxidation, and white-to-brown adipocyte differentiation, while showing a negative correlation with pro-adipogenic genes (95, 161)

& De Jonghe, B