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Genetic variants within or near the GLP1R gene associated with BMI or HbA1c at genome-wide significance were used for primary analyses
Store Paste below 30C (Room Temperature)
The alanine at position 8, the residue immediately adjacent to the DPP-4 cleavage bond, is replaced by alpha-aminoisobutyric acid (Aib), a non-canonical, doubly methylated amino acid whose steric bulk blocks protease access [1]
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Examples of research applications include: Peptide signalling pathway investigation Receptor interaction research Intracellular signalling modelling Comparative peptide studies Molecular pathway analysis Controlled in vitro research Laboratory signalling studies Grail Formula Quality Every Grail Formula research compound is produced under strict quality control procedures designed to support reliable laboratory experimentation
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