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Key developments expected in the coming months include: Near-Term Milestones Bellwether Trial Selection Representative cases will be chosen for early trial Expert Testimony Medical experts will testify on causation and drug safety Document Discovery Internal company communications under review Looking Ahead Settlement Talks If bellwether trials favor plaintiffs, Novo Nordisk may negotiate global settlements MDL Expansion New claims involving hair loss, kidney injury, and emotional distress are being evaluated First Trials Expected to begin in early 2026 Legal analysts expect the first bellwether trials to begin in early 2026, potentially setting precedent for thousands of future claims

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The clinical expert also noted that the definition of MACE used in PIONEER 6, which included CV death, non-fatal MI or non-fatal stroke, was relevant to clinical practice