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The cardioprotective effect of metformin in patients with type 2 diabetes is not only attributable to its glucose-lowering effects but also to its significant antihypertensive properties [33]

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Plasma homocysteine, methionine and S-adenosylhomocysteine levels following high-dose methotrexate treatment in pediatric patients with acute lymphoblastic leukemia or Burkitt lymphoma: association with hepatotoxicity